Device Descrikptor Request Failed

Charles, For your info, just in case that you are unaware, you can post the screenshot here in your topic. Click on 'Answer' & then click on the 'Image' [mountain symbol] & follow the instructions. 
AVG Guru

Hello Charles,

Could you share the screenshot http://support.avg.com/SupportArticleView?urlname=How-to-create-a-screenshot of that message received on PC Tuneup to have better understanding?

You can click on ignore option or try repair http://support.avg.com/SupportArticleView?urlname=How-to-repair-AVG installation of AVG PC Tuneup and check its status.

So I am running pc tuneujp on a windows 10 pc and I get the following problem found:  The driver for  "Unknown USB Device (Device Descriptor Request Failed) is not working properly'  Have run Driver Updater with no success and a scan of the hard drive.  I can ignore or Open, If I open Driver Updater runs and finds no problem.  What do I do with this?

Charles, For your info, just in case that you are unaware, you can post the screenshot here in your topic. Click on 'Answer' & then click on the 'Image' [mountain symbol] & follow the instructions. 
AVG Guru

Hello Charles,

Could you share the screenshot http://support.avg.com/SupportArticleView?urlname=How-to-create-a-screenshot of that message received on PC Tuneup to have better understanding?

You can click on ignore option or try repair http://support.avg.com/SupportArticleView?urlname=How-to-repair-AVG installation of AVG PC Tuneup and check its status.